Figure 2.

Diagnostic algorithm for hepatocellular carcinoma using multiple modalities according to Asian Pacific Association for the Study of the Liver (APASL). Reprint with permission from Omata et al [8]. US, ultrasonography; EOB, gadoxetate disodium; CT, computed tomography; HCC, hepatocellular carcinoma; CEUS, contrast enhanced ultrasonography; DN, dysplastic nodule. *Cavernous hemangioma sometimes shows hypointensity on the equilibrium (transitional) phase of dynamic Gd-EOB DTPA magnetic resonance imaging (MRI) (pseudo-wash-out). It should be excluded by further MRI sequences and/or other imaging modalities; ^† Cavernous hemangioma usually shows hypointensity on the hepatobiliary phase of Gd-EOB DTPA MRI. It should be excluded by other MRI sequences and/or other imaging modalities.