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. 2019 Sep 25;7(18):e14234. doi: 10.14814/phy2.14234

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© 2019 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Susceptibility to HIV‐1 infection was increased in postexercise samples. (A) Example replication curve from one subject. Virus replication is presented as RT activity measured from cell culture supernatants (arbitrary units). (B) Plots show fold changes in HIV‐1 replication levels in the activated CD4⁺ T cells in each subject between control (0.02 ± 0.34) and exercise (0.29 ± 0.38) sessions at 3 days post infection. (C) The median fluorescence intensity (MFI) was determined for CD4 expression (Control: 0.46 ± 1.6, Exercise: 0.61 ± 1.5) following 3 days stimulation with anti‐CD3 and anti‐CD28. Data are presented as fold change from baseline and visualized as spaghetti plots with each line representing the change between paired samples; n = 10. *Indicates a statistically significant difference (P < 0.05) from the control session.