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. 2019 Sep 18;10:1145. doi: 10.3389/fphys.2019.01145

FIGURE 4.

FIGURE 4

The effect of diuretic treatment added to combined RAS and ETA blockade on relative kidney weight and glomerular area. Relative kidney weight (A) and glomerular area (B) in sham-operated heterozygous Ren-2 transgenic rats (TGR-sham), nephrectomized TGR (TGR-NX) treated with the renin-angiotensin system blockade alone (RAS), combined RAS + ETA blockade (RAS + ETA); or diuretic given with the combined RAS + ETA blockade (RAS + ETA + Diu). # P < 0.05 TGR-sham vs. other TGR-NX-treated groups, Diu – diuretic. # P < 0.05 TGR-sham vs. other TGR-NX-treated groups, @ P < 0.05 TGR-NX + RAS + ETA + diuretic vs. other TGR-NX-treated groups.