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. 2019 Sep 25;7(18):e14239. doi: 10.14814/phy2.14239

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© 2019 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Effect of a low calorie diet (LCD) and low calorie diet plus interval exercise (LCD + INT) interventions on relative fasting (A) and 120 minute incremental area under the curve (iAUC_120min) (B) flow mediated dilation (FMD) in all study participants. Effect of LCD and LCD + INT interventions on relative fasting (C) and iAUC_120min (D) FMD in study participants in the lower (Δ < 50%; LCD n = 7, LCD + INT n = 6) and upper (Δ> 50%; LCD n = 5, LCD + INT n = 7) 50th percentile. Bars are presented as mean ± standard error of the mean (SEM). Grey lines are individual data points pre‐intervention (PRE) to post‐intervention (POST). † Denotes a significant (P ≤ 0.005) difference from Δ > 50th% LCD.