Table III.
Storage time cut-offs for FFPE tissue blocks based on dsDNA quantity (n=218) and ∆Cp value (n=214).
| A. Depending on dsDNA quantity (n=218). | |||||
|---|---|---|---|---|---|
| N (%) | dsDNA ≥ median (%) | ||||
| Cut-off (years) | <Cut-off | ≥Cut-off | <Cut-off | ≥Cut-off | P-value |
| 2 | 6 (2.75) | 212 (97.25) | 83.3 | 49.1 | 0.1061 |
| 3 | 35 (16.06) | 183 (83.94) | 77.1 | 44.8 | 0.0004 |
| 4 | 73 (33.49) | 145 (66.51) | 69.9 | 40.0 | <0.0001 |
| 5 | 123 (56.42) | 95 (43.58) | 59.4 | 40.7 | 0.0013 |
| 6 | 172 (78.90) | 46 (21.10) | 51.7 | 43.5 | 0.2034 |
| 7 | 192 (88.07) | 26 (11.93) | 50.5 | 46.2 | 0.4174 |
| 8 | 205 (94.00) | 13 (5.96) | 51.2 | 30.8 | 0.1260 |
| B. Depending on ∆Cp value (n=214). | |||||
| N (%) | ΔCp ≥ median (%) | ||||
| Cut-off (years) | <Cut-off | ≥Cut-off | <Cut-off | ≥Cut-off | P-value |
| 2 | 6 (2.80) | 208 (97.20) | 100.0 | 48.6 | 0.0145 |
| 3 | 34 (15.89) | 180 (84.11) | 79.4 | 44.4 | 0.0001 |
| 4 | 71 (33.18) | 143 (66.82) | 64.8 | 42.7 | 0.0018 |
| 5 | 120 (56.07) | 94 (43.93) | 60.0 | 37.2 | 0.0007 |
| 6 | 168 (78.50) | 46 (21.50) | 53.6 | 37.0 | 0.3322 |
| 7 | 188 (87.85) | 26 (12.15) | 53.2 | 26.9 | 0.0100 |
| 8 | 201 (93.93) | 13 (6.07) | 51.2 | 30.8 | 0.1259 |