Table III.

Characteristics of the genotyped SNPs of the ADIPOQ and EDN1 genes.

A, ADIPOQ
No.	SNP	Location (GRCh38.p12)	Relation	Major/minor allele	MAF EUR	Observed MAF	Pairwise r2 of linkage disequilibriuma
1	rs17366743	3:186854300	Exon 3 coding non-synonymous	T/C	0.04	0.02	0.04(1-3); 0.05(1-4); 0.03(1-5)
2	rs17300539	3:186841671	Promoter	G/A	0.07	0.07	0.02(2-3); 0.04(2-4)
3	rs266729	3:186841685	Promoter	C/G	0.28	0.29	0.64(3-4)b; 0.02(3-5)
4	rs182052	3:186842993	Intron	G/A	0.39	0.38	0.04(4-5)
5	rs2241766	3:186853103	Exon 2 coding non-synonymous	T/G	0.13	0.06
B, EDN1
No.	SNP	Location (GRCh38.p12)	Relation to gene	Major/minor allele	MAF EUR	Observed MAF	Pairwise r2 of linkage disequilibriuma
1	rs2070699	6:12292539	Intron	G/T	0.47	0.5	0.04(1-2); 0.23(1-3)
2	rs1800542	6:12292295	Intron	G/A	0.04	0.04
3	rs1800543	6:12293904	Intron	T/C	0.22	0.21

^aReported for P<0.05, SNP numbers in brackets;

^bPotential linkage between the SNPs indicated in brackets. SNP, single-nucleotide polymorphism;ADIPOQ, adiponectin; EDN1, endothelin-1; GRCh38.p12, Genome Reference Consortium human build 38 patch release 12; MAF, minor allele frequency; MAF EUR, European MAF according to Ensembl release 95.