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. 2019 Sep 18;6:300. doi: 10.3389/fvets.2019.00300

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Copyright © 2019 Setthawongsin, Teewasutrakul, Tangkawattana, Techangamsuwan and Rungsipipat.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Localization of Ki-67, Bcl-2, and Bax. Ki-67 localized in the nucleus of TVT cells (A). Bcl-2 localized in nuclear membrane and cytoplasm of CTVT cells (B). Bax localized in the cytoplasm of CTVT cells (C) (LSAB-IHC method, DAB counterstained with Mayer, hematoxylin, bar = 20 μm). Histopathology pictures of CTVT in progression phase and regression phase. CTVT during growth phase (D,G), the section shown the numerous CTVT cells. CTVT during early regression phase (E,H), the section showed the moderate amount of CTVTs and presented the tumor infiltrated lymphocytes (TILs). CTVT during the late stage of regression phase (F,I), fibrous tissue which replaced the CTVT parenchyma (H&E stain, bar = 20 μm) (Masson Trichrome stain, bar = 20 μm).