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. 2019 Sep 18;9:898. doi: 10.3389/fonc.2019.00898

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Copyright © 2019 Yang, Shen, Xu, Chen, Che, Qu, Liu, Teng and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The seed lncRNAs were extracted by 1,000 times Cox LASSO regression. (A) Highly consistency was demonstrated in the lncRNAs among the 8 extracted lncRNA sets. The left ordinate indicates the seed lncRNA set and the number of seeds lncRNAs found by every single iteration of LASSO. The right ordinate is the frequency of the seed lncRNA set disclosed through the 1,000 times Cox LASSO regression. The horizontal ordinate is the lncRNA name. The yellow block represents the occurrence of the particular lncRNA in the specific lncRNA set; (B) Totally 28 seed lncRNAs with >990 occurrences in the most common lncRNA set were filtered out for further analysis. The blue column indicates the frequency of each lncRNA occurs in the most common lncRNA set.