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. 2019 Sep 18;10:1171. doi: 10.3389/fphys.2019.01171

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Copyright © 2019 Reynés, van Schothorst, Keijer, Ceresi, Oliver and Palou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Volcano Plot for all expressed probes by microarray analysis in tPVAT (A) and IAT (C). Minus log10 p-value of all genes are plotted against the differences of group means (log ratio) of each gene, cold vs. control. The line indicates the threshold p-value < 0.05. Detailed manual classification of the 50 top up- and down-regulated genes based on their fold change (Student’s t-test, p-value < 0.05) in tPVAT (B) and in IAT (D). The results represent data from the control (n = 7) and cold (n = 6–7) groups.