Table 4.
Adjusted mixed‐effects regression models for absolute changes in mean systolic blood pressures, UGANDAC study 2019
|
Model 1 Coeff (95% CI) |
Model 2 Coeff (95% CI) |
Model 3 Coeff (95% CI) |
Model 4 Coeff (95% CI) |
|
|---|---|---|---|---|
| Model parameters | ||||
| AIC (df) | 7581.9 (16) | 7572.2 (18) | 7379.307 (20) | 4849.07 (17) |
| BIC | 7659.8 | 7659.8 | 7476.2 | 4924.18 |
| β0 coefficient | 106.6 (96.1, 117.1)*** | 108.3 (97.8, 118.8)*** | 108.4 (96.4, 120.3)*** | 85.13 (66.80, 103.46)*** |
| Characteristic | ||||
| Age (y) | 0.2 (0.1, 0.4)* | 0.3 (0.1, 0.5)** | 0.3 (0.1, 0.4)* | 0.300 (0.09, 0.51)** |
| Men | Ref | Ref | Ref | Ref |
| Women | −3.1 (−6.1, −0.2)* | −4.4 (−7.41, −1.3)** | −4.5 (−7.5, −1.4)** | −3.79 (−7.13, −0.45)* |
| HIV serostatus and year | ||||
| HIV‐uninfected year 0 | Ref | Ref | Ref | Ref |
| HIV‐uninfected year 1 | −5.7 (−8.0, −3.5)*** | −5.8 (−8.1, −3.6)*** | −6.0 (−8.2, −3.7)*** | −6.46 (−9.17, −3.75)*** |
| HIV‐uninfected year 2 | −5.5 (−8.0, −2.9)*** | −5.6 (−8.1, −3.1)*** | −5.8 (−8.4, −3.2)*** | −5.56 (−8.94, −2.17)** |
| HIV‐uninfected year 3 | −4.1 (−7.4, −0.8)* | −4.6 (−7.9, −1.3)** | −4.6 (−7.5, −1.3)** | |
| HIV‐uninfected year 4 | 0.9 (−7.0, 8.7) | −0.1 (−8.0, 7.8) | −0.2 (−8.1, 7.7) | |
| HIV‐infected Year 0 | −6.7 (−10.3, −3.1)*** | −7.5 (−11.1, −3.9)*** | −8.0 (−11.6, −4.3)*** | −7.82 (−11.47, −4.17)*** |
| HIV‐infected year 1 | −7.0 (−10.6, −3.5)*** | −7.9 (−11.4, −4.3)*** | −8.4 (−12.0, −4.8)*** | −7.88 (−11.50, −4.26)*** |
| HIV‐infected year 2 | −6.7 (−10.3, −3.1)*** | −7.5 (−11.1, −3.8)*** | −7.6 (−11.3, −4.0)*** | −8.68 (−12.49, −4.88)*** |
| HIV‐infected year 3 | −4.2 (−8.2, −0.3)* | −5.2 (−9.2, −1.1)* | −5.4 (−9.4, −1.3)** | |
| HIV‐infected year 4 | −1.6 (−7.0, 3.8) | −2.4 (−7.8, 3.0) | −2.5 (−7.9, 3.0) | |
| Smoking, n (%) | ||||
| Never | Ref | Ref | Ref | |
| Current | −5.5 (−9.3, −1.7)** | −5.4 (−9.2, −1.6)** | −5.3 (−9.7, −0.9)* | |
| Former | −1.1 (−3.6, 1.4) | −1.0 (−3.5, 1.6) | −1.2 (−4.1, 1.6) | |
| Physical activity | ||||
| Low‐intensity activity | Ref | Ref | ||
| Moderate activity | 1.3 (−5.7, 8.3) | 0.3 (−7.6, 8.3) | ||
| Vigorous activity | 0.1 (−5.2, 5.4) | −2.2 (−7.9, 3.5) | ||
| Serum albumin (per 1 g/dL) | 5.3 (2.3, 8.4)*** | |||
Coefficient represents the difference in BP change (in mm Hg) between the category of interest and the reference category;
Low‐intensity activity (activity with <3 metabolic equivalents (MET) h/wk; moderate activity (activity with 3 to <6 MET h/wk); vigorous activity (activity with ≥6 METS h/wk).
Abbreviations: AIC: Akaike's information criterion; BIC: Bayesian information criterion.
*
P < 0.05;
**
P < 0.01;
***
P < 0.001.