Table 5.
Adjusted mixed‐effects regression models for absolute changes in mean diastolic blood pressures, UGANDAC study 2019
|
Model 1 Coeff (95% CI) |
Model 2 Coeff (95% CI) |
Model 3 Coeff (95% CI) |
Model 4 Coeff (95% CI) |
|
|---|---|---|---|---|
| AIC (df) | 6855.1 (16) | 6841.78 (18) | 6663.35 (20) | 4354.0 (17) |
| BIC | 6920.0 | 6914.8 | 6744.5 | 4423.0 |
| β0 coefficient | 75.7 (68.7, 82.7)*** | 77.2 (70.3, 84.2)*** | 78.7 (70.8, 86.7)*** | 66.2 (54.1, 78.4)*** |
| Characteristic | ||||
| Age (y) | −0.1 (−0.1, 0.1) | 0.1 (−0.1, 0.1) | 0.1 (−0.1, 0.1) | 0.1 (−0.1, 0.1) |
| Men | Ref | Ref | Ref | Ref |
| Women | 0.5 (−1.4, 2.4) | −0.7 (−2.7, 1.3) | −0.6 (−2.6, 1.3) | 0.5 (−1.7, 2.7) |
| HIV serostatus and year | ||||
| HIV‐uninfected Year 0 | Ref | Ref | Ref | Ref |
| HIV‐uninfected Year 1 | −4.6 (−6.2, −3.0)*** | −4.7 (−6.3, −3.1)*** | −4.7 (−6.3, −3.1)*** | −5.6 (−7.4, −3.9)*** |
| HIV‐uninfected Year 2 | −3.4 (−5.2, −1.7)*** | −3.6 (−5.3, −1.8)*** | −3.7 (−5.4, −1.9)*** | −4.9 (−7.1, −2.7)*** |
| HIV‐uninfected Year 3 | −0.8 (−2.9, 1.4) | −1.1 (−3.2, 1.1) | −0.9 (−3.1, 1.3) | |
| HIV‐uninfected Year 4 | 0.6 (−4.6, 5.8) | 0.1 (−5.2, 5.3) | 0.3 (−5.0, 5.7) | |
| HIV‐infected Year 0 | −5.6 (−8.0, −3.1)*** | −6.2 (−8.6, −3.8)*** | −6.6 (−9.1, −4.2)*** | −6.4 (−8.8, −3.9)*** |
| HIV‐infected Year 1 | −6.4 (−8.8, −4.0)*** | −7.1 (−9.5, −4.7)*** | −7.4 (−9.8, −5.0)*** | −6.9 (−9.3, −4.5)*** |
| HIV‐infected Year 2 | −4.0 (−6.5, −1.6)** | −4.7 (−7.1, −2.2)*** | −4.7 (−7.1, −2.2)*** | −5.4 (−7.9, −2.9)*** |
| HIV‐infected Year 3 | −2.3 (−5.0, 0.3) | −3.1 (−5.7, −0.4)* | −3.0 (−5.7, −0.4)* | |
| HIV‐infected Year 4 | −0.1 (−3.7, 3.4) | −0.7 (−4.3, 2.8) | −0.8 (−4.4, 2.8) | |
| Smoking, n (%) | ||||
| Never | Ref | Ref | Ref | |
| Current | −4.8 (−7.3, −2.2)*** | −4.6 (−7.2, −2.1)*** | −4.2 (−7.1, −1.3)** | |
| Former | −1.9 (−3.6, −0.2)* | −2.0 (−3.7, −0.3)* | −2.0 (−3.9, −0.1)* | |
| Physical activity | ||||
| Low‐intensity activity | Ref | Ref | ||
| Moderate activity | 0.1 (−4.8, 4.8) | −0.7 (−4.0, 4.6) | ||
| Vigorous activity | −1.5 (−5.2, 2.1) | −2.7 (−6.5, 1.1) | ||
| Serum Albumin (per 1 g/dL) | 2.9 (0.9, 4.9)** | |||
Coefficient represents the difference in BP change (in mm Hg) between the category of interest and the reference category; low‐intensity activity (activity with <3 metabolic equivalents (MET) h/wk; moderate activity (activity with 3 to <6 MET hours/week); vigorous activity (activity with ≥6 METS h/wk).
Legend:
Abbreviations: AIC: Akaike's information criterion; BIC: Bayesian information criterion.
*
P < 0.05;
**
P < 0.01;
***
P < 0.001.