TABLE 4.

Soleus miRNA molecules with significant difference related to intrinsic exercise capacity.

miRNA molecules	Biological functions	Fold change (HEC/LEC)	p-value
miR-383	(1) Testosterone and progesterone regulation, (2) spermatogenesis, and (3) steroidogenesis	18.43	1.18E−03
miR-107	Insulin sensitivity	4.55	3.68E−01
miR-30b	Role of regeneration	3.98	2.54E−03
miR-669m	Adaptation during toxic metabolites accumulation	3.92	4.72E−02
miR-191	Adipogenesis inhibition	3.68	3.08E−01
miR-218	Vascular organization	3.31	2.00E−01
miR-224	Adipogenesis regulation (fatty acid metabolism)	3.04	8.47E−02

The significant difference (p < 0.05) for high exercise capacity (HEC) and low exercise capacity (LEC) groups was compared by t-test.