TABLE 4.
Strain | Regimen |
Mean PAE (h) ± SD |
||
0.25 MIC | 0.5 MIC | 1 MIC | ||
S. aureus SA1199B | Ciprofloxacin | 0.43 ± 0.14 | 1.05 ± 0.19 | 1.43 ± 0.16 |
Ciprofloxacin + RP2 (32 μg/mL) | 1.68 ± 0.13 | 2.15 ± 0.15 | 3.33 ± 0.18 | |
S. aureus XU212 | Tetracycline | 0.76 ± 0.13 | 1.2 ± 0.17 | 2.1 ± 0.14 |
Tetracycline + RP2 (32 μg/mL) | 1.93 ± 0.12 | 2.45 ± 0.08 | 3.4 ± 0.25 | |
S. aureus RN4220-MsrA | Erythromycin | 0.46 ± 0.13 | 1.08 ± 0.17 | 1.82 ± 0.14 |
Erythromycin + RP2 (32 μg/mL) | 1.77 ± 0.12 | 2.24 ± 0.08 | 3.32 ± 0.25 |
The results presented correspond to the average of three independent assays plus standard deviation (±SD).