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. 2019 Sep 18;10:2153. doi: 10.3389/fmicb.2019.02153

TABLE 4.

PAE of ciprofloxacin, tetracycline, and erythromycin alone and in combination with RP2 against S. aureus SA1199B, XU212 and RN4220-MsrA, respectively.

Strain Regimen Mean PAE (h) ± SD
0.25 MIC 0.5 MIC 1 MIC
S. aureus SA1199B Ciprofloxacin 0.43 ± 0.14 1.05 ± 0.19 1.43 ± 0.16
Ciprofloxacin + RP2 (32 μg/mL) 1.68 ± 0.13 2.15 ± 0.15 3.33 ± 0.18
S. aureus XU212 Tetracycline 0.76 ± 0.13 1.2 ± 0.17 2.1 ± 0.14
Tetracycline + RP2 (32 μg/mL) 1.93 ± 0.12 2.45 ± 0.08 3.4 ± 0.25
S. aureus RN4220-MsrA Erythromycin 0.46 ± 0.13 1.08 ± 0.17 1.82 ± 0.14
Erythromycin + RP2 (32 μg/mL) 1.77 ± 0.12 2.24 ± 0.08 3.32 ± 0.25

The results presented correspond to the average of three independent assays plus standard deviation (±SD).