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. 2019 Sep 18;10:1051. doi: 10.3389/fphar.2019.01051

Table 2.

Duration of action potentials in isolated perfused mouse hearts from WT.

WT CGS21680 Stem CGS21680 WT BASE Stem BASE p-values N WT CGS21680 N WT BASELINE
80 ARD90 23.4 2.2 31.4 1.6 0.073 3 7
ARD70 11.9 1.0 17.6 1.6 0.027 3 7
ARD50 8.2 0.9 12.0 1.2 0,065 3 7
AT 13.1 0.6 13.9 1.4 0.67 3 7
100 ARD90 23.7 0.8 32.5 2.0 0.006 4 7
ARD70 12.4 0.8 18.9 1.6 0.013 3 7
ARD50 8.4 0.6 12.8 1.3 0.025 3 7
AT 13.2 0.4 13.7 1.1 0.699 4 7
120 ARD90 26.3 4.5 33.8 2.4 0.306 3 6
ARD70 15.6 3.2 20.4 2.0 0.356 3 6
ARD50 10.6 2.3 13.7 1.6 0.41 3 6
AT 13.9 1.2 13.8 1.3 0.957 3 6

Cycle length of 80, 100, and 120 ms (first column) under basal conditions (basal) and after application of 1 µM CGS 21680.