Table 3.
Predictors of MACE in Univariate and Multivariable Cox Regression Analysis
| Variable | Univariate | Stepwise Multivariable | ||
|---|---|---|---|---|
| HR (95% CI) | P Value | HR (95% CI) | P Value | |
| Age, y | 1.05 (1.03–1.07) | <0.001 | 1.04 (1.02–1.07) | 0.002 |
| Male sex | 0.59 (0.37–0.96) | 0.032 | ··· | ··· |
| Current smoking | 0.53 (0.31–0.90) | 0.018 | ··· | ··· |
| Diabetes mellitus | 1.93 (1.20–3.12) | 0.007 | ··· | ··· |
| Hypertension | 2.36 (1.24–4.48) | 0.009 | ··· | ··· |
| Killip class on admission | 2.04 (1.61–2.58) | <0.001 | 1.47 (1.05–2.04) | 0.024 |
| Number of diseased vessels | 1.51 (1.15–2.00) | 0.004 | ··· | ··· |
| LVEF (%) | 0.94 (0.92–0.96) | <0.001 | 0.94 (0.92–0.97) | <0.001 |
| Infarct size (% LV) | 1.03 (1.01–1.05) | <0.001 | ··· | ··· |
| Microvascular obstruction (% LV) | 1.09 (1.03–1.15) | 0.003 | ··· | ··· |
| CURE <0.84* | 2.42 (1.47–3.98) | 0.001 | ··· | ··· |
| RURE <0.75* | 2.17 (1.34–3.53) | 0.002 | ··· | ··· |
CURE indicates circumferential uniformity ratio estimate; HR, hazard ratio; LVEF, left ventricular ejection fraction; MACE, major adverse cardiac events; % LV indicates percentage of left ventricular mass; RURE, radial uniformity ratio estimate.
*
Cutoffs for CURE and RURE are median values in the study population.