Table 4.
Predictors of MACE in Patients With Ejection Fraction >35%
| Variable | Univariate | Stepwise Multivariable | ||
|---|---|---|---|---|
| HR (95% CI) | P Value | HR (95% CI) | P Value | |
| Age, y | 1.05 (1.02–1.08) | <0.001 | 1.04 (1.01–1.07) | 0.006 |
| Male sex | 0.53 (0.30–0.96) | 0.035 | ··· | ··· |
| Current smoking | 0.46 (0.23–0.92) | 0.027 | ··· | ··· |
| Diabetes mellitus | 2.75 (1.55–4.86) | 0.001 | ··· | ··· |
| Hypertension | 2.14 (1.00–4.58) | 0.049 | ··· | ··· |
| Killip class on admission | 1.87 (1.33–2.63) | <0.001 | ··· | ··· |
| Number of diseased vessels | 1.59 (1.13–2.24) | 0.009 | 1.61 (1.09–2.38) | 0.016 |
| LVEF (%) | 0.96 (0.92–0.99) | 0.013 | ··· | ··· |
| Infarct size (% LV) | 1.03 (1.00–1.05) | 0.029 | ··· | ··· |
| CURE <0.84* | 2.57 (1.41–4.68) | 0.002 | 1.99 (1.06–3.74) | 0.033 |
CURE indicates circumferential uniformity ratio estimate; HR, hazard ratio; LVEF, left ventricular ejection fraction; MACE, major adverse cardiac events; % LV indicates percentage of left ventricular mass.
*
The cutoff for CURE is the median value in the study population.