HspB1 (Hsp27) |
Protein (Quraishe et al., 2008) mRNA (Kirbach and Golenhofen, 2011) |
Heat (Kirbach and Golenhofen, 2011) Oxidative (Bartelt-Kirbach and Golenhofen, 2014; Bartelt-Kirbach et al., 2017) |
Aβ (Ojha et al., 2011b) tau (Shimura et al., 2004; Freilich et al., 2018) α-Syn (Bruinsma et al., 2011; Cox et al., 2018) SOD-1 (Yerbury et al., 2013) TDP-43 (Wan et al., 2015) |
↑Aβ (Ojha et al., 2011b) ↓Aβ (Wilhelmus et al., 2006a; Yoshiike et al., 2008) ↓Tau (Abisambra et al., 2010; Baughman et al., 2018; Freilich et al., 2018; Mok et al., 2018) ↓α-Syn (Bruinsma et al., 2011; Cox et al., 2018) ↓ polyQ (Vos et al., 2010) |
AD (Wilhelmus et al., 2006c; Björkdahl et al., 2008; Yu et al., 2018) HD (Brehme et al., 2014) PD ( Zhang et al., 2005; Brehme et al., 2014) |
HspB2 (MKBP) |
mRNA (Kirbach and Golenhofen, 2011) |
|
α-Syn (Bruinsma et al., 2011) |
↓α-Syn (Bruinsma et al., 2011) |
AD (Wilhelmus et al., 2006c; Yu et al., 2018) HD (Brehme et al., 2014) PD (Brehme et al., 2014) |
HspB3 (Hsp17) |
mRNA (Kirbach and Golenhofen, 2011) |
|
|
|
AD (Brehme et al., 2014) |
HspB4 (αA-crystallin) |
|
|
|
↓ polyQ (Vos et al., 2010) |
|
HspB5 (αB-crystallin) |
Protein (Quraishe et al., 2008) mRNA (Kirbach and Golenhofen, 2011) |
Heat (Kirbach and Golenhofen, 2011) Oxidative (Bartelt-Kirbach and Golenhofen, 2014; Bartelt-Kirbach et al., 2017 ) |
Aβ (Shammas et al., 2011) α-Syn (Rekas et al., 2004; Waudby et al., 2010; Bruinsma et al., 2011; Cox et al., 2018) polyQ (Robertson et al., 2010) SOD-1 (Yerbury et al., 2013) |
↓Aβ (Wilhelmus et al., 2006a; Shammas et al., 2011) ↓α-Syn (Rekas et al., 2004; Waudby et al., 2010; Bruinsma et al., 2011) |
AD (Wilhelmus et al., 2006c; Björkdahl et al., 2008) HD (Brehme et al., 2014) PD (Brehme et al., 2014) ALS (Gorter et al., 2018) |
HspB6 (Hsp20) |
Protein (Quraishe et al., 2008) mRNA (Kirbach and Golenhofen, 2011) |
Oxidative (Bartelt-Kirbach and Golenhofen, 2014) |
Aβ (Cameron et al., 2014) α-Syn (Bruinsma et al., 2011) |
↓Aβ (Wilhelmus et al., 2006a) ↓α-Syn (Bruinsma et al., 2011) ↓ polyQ (Vos et al., 2010) |
AD (Wilhelmus et al., 2006c) |
HspB7 (cvHsp) |
Protein (Uhlén et al., 2015) mRNA (Quraishe et al., 2008) |
|
|
↓↓ polyQ (Vos et al., 2010) |
|
HspB8 (Hsp22) |
Protein (Quraishe et al., 2008) mRNA (Kirbach and Golenhofen, 2011) |
Heat (Kirbach and Golenhofen, 2011) Oxidative (Bartelt-Kirbach and Golenhofen, 2014) |
Aβ (Wilhelmus et al., 2006b) α-Syn (Bruinsma et al., 2011) |
↓Aβ (Wilhelmus et al., 2006b) ↓ α-Syn (Bruinsma et al., 2011) ↓ polyQ (Vos et al., 2010) |
AD (Brehme et al., 2014; Wilhelmus et al., 2006b) HD (Brehme et al., 2014) ALS (Gorter et al., 2018) |
HspB9 (CT51) |
|
|
|
↓ polyQ (Vos et al., 2010) |
|
HspB10 (ODFP1) |
|
|
|
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