Table 1.
Suggestive SNP association signals for Aurora.
| SNP | Chr | Position (bp) | Min/Maj | MAF | B | SE | P | Phenotype | Gene |
|---|---|---|---|---|---|---|---|---|---|
| rs7523543 | 1 | 25,186,716 | G/A | 0.37 | -5.19 | 1.15 | 9.52 × 10-6 | Aurora-N | LOC105376876 (intron) |
| rs4234535 | 3 | 16,162,533 | A/G | 0.28 | -5.24 | 1.16 | 8.84 × 10-6 | Aurora-N | GALNT15 (upstream of) |
| rs9765600 | 5 | 119,919,047 | A/C | 0.40 | -5.18 | 1.04 | 1.12 × 10-6 | Aurora-N | PRR16 (intron) |
| -4.64 | 1.00 | 4.97 × 10-6 | Aurora-V | ||||||
| rs79027391 | 6 | 12,122,102 | G/T | 0.02 | -20.01 | 4.08 | 1.46 × 10-6 | Aurora-F | HIVEP1 (missense) |
| rs2806225 | 6 | 7,579,412 | T/C | 0.24 | 6.16 | 1.28 | 2.41 × 10-6 | Aurora-N | DSP (intron) |
| rs1863004 | 7 | 135,053,638 | G/A | 0.24 | -5.73 | 1.27 | 8.60 × 10-6 | Aurora-N | CNOT4 (intron) |
| rs2651374 | 12 | 32,582,858 | C/T | 0.46 | -5.10 | 1.05 | 1.91 × 10-6 | Aurora-F | FGD4 (intron) |
| rs4771493 | 13 | 105,927,432 | C/T | 0.32 | 5.24 | 1.16 | 8.57 × 10-6 | Aurora-N | LOC105370344 (upstream of) |
| rs1160549 | 14 | 80,464,509 | C/T | 0.13 | 6.88 | 1.49 | 5.49 × 10-6 | Aurora-F | NRXN3 (downstream from) |
| rs9935286 | 16 | 12,594,359 | C/T | 0.22 | 5.97 | 1.32 | 7.86 × 10-6 | Aurora-N | SNX29 (intron) |
| rs9910269 | 17 | 75,049,645 | T/C | 0.24 | -5.18 | 1.15 | 9.53 × 10-6 | Aurora-G | SEC14L1 (upstream of) |
Min, minor allele; Maj, major allele; MAF, minor allele frequency; B, effect size estimate; SE, standard error; P, Wald p value (uncorrected); Phenotypes: Aurora-G, general cognitive ability; Aurora-V, verbal cognitive ability; Aurora-N, numerical cognitive ability; Aurora-F, figural cognitive ability.