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. 2019 Sep 18;6:314. doi: 10.3389/fvets.2019.00314

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Copyright © 2019 Sandercock, Barnett, Coe, Downing, Nirmal, Di Giminiani, Edwards and Freeman.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Network analysis of gene expression data. (A) Co-expression graph (r ≥ 0.75) with two clusters, A and B, highlighted. Cluster A (highlighted in green) contains 759 transcripts whose expression was down-regulated following tail docking and comprising many genes associated with neuronal function. Cluster B (highlighted in purple) contains 273 transcripts consistently upregulated following tail docking and comprising many genes associated with wound healing. (B) Histograms of mean expression profiles for cluster A (green) and cluster B (purple), each bar representing data from a single animal.