Table 1.

Total number of significant (P < 0.05) differentially expressed genes (up and down regulated) in caudal DRG neurons using an RMA 3-way-ANOVA contrast on tail amputated vs. sham-treated pigs undergoing tail treatment at 3 (neonatal) and 63 (juvenile) days of age (1, 8, and 16 weeks after tail treatment) with false discovery rate (FDR) = 0.05 applied (8^* pigs/treatment/age/time).

Tail amputated vs. sham treatment
Treatment age	Time after treatment	Differentially expressed genes (FDR = 0.05)	Up regulated	Down regulated
3 days	1 week	518	351	167
	8 weeks	2,268	788	1,480
	16 weeks	119	89	30
63 days	1 week	1,530	918	612
	8 weeks	3,794	1,937	1,857
	16 weeks	780	569	211

^*Except for 63 day sham-treated T+1 week where n = 7 due to the removal of a tail bitten pig.