Table 2.

Association of baseline variables with plasma suPAR levels, measured by two independent ELISA tests, in FSGS patients.

Variable	Regression coefficient (95% CI) with suPAR adjusteda suPARnostic™ assay*	P-value	Regression coefficient (95% CI) with suPAR adjusteda Quantikine Human uPAR ELISA Kit**	P-value
Gender (male)	−0.598 (−1.748 to 0.553)	0.302	−0.341 (−0.876 to 0.193)	0.205
Age (years)	0.009 (−0.028 to 0.046)	0.641	0.015 (−0.002 to 0.032)	0.089
eGFR (mL/min/1.73 m2)	−0.043 (−0.061 to −0.025)	0.001	−0.018 (−0.026 to −0.010)	0.001
Serum creatinine (mg/dL)	0.074 (−0.576 to 0.428)	0.769	−0.001 (−0.234 to 0.233)	0.996
Serum albumin (g/dL)	0.003 (−0.099 to 0.105)	0.952	−0.002 (−0.049 to 0.046)	0.941
Serum C-reactive protein (mg/dL)	0.492 (−0.661 to 1.645)	0.395	0.101 (−0.438 to 0.640)	0.709
Serum total cholesterol (mg/dL)	−0.004 (−0.014 to 0.006)	0.435	−0.001 (−0.005 to 0.004)	0.757
Urine protein/creatinine ratio (mg/g)	0.001 (−0.001 to 0.001)	0.142	0.001 (−0.001 to 0.001)	0.100
Urine albumin/creatinine ratio (mg/g)	0.001 (−0.001 to 0.002)	0.871	−0.001 (−0.001 to 0.002)	0.942
Presence of microscopic hematuria	−0.466 (−2.222 to 1.290)	0.595	−0.133 (−0.927 to 0.661)	0.738
Presence of hypertension	−1.843 (−4.227 to 0.541)	0.125	−0.026 (−1.130 to 1.077)	0.961
Presence of diabetes	0.855 (−0.726 to 2.437)	0.280	0.476 (−0.200 to 1.151)	0.162
History of renal transplantation	0.592 (−0.611 to 1.795)	0.327	0.111 (−0.453 to 0.674)	0.695
Duration of disease (months)	0.023 (−0.099 to 0.146)	0.702	0.026 (−0.031 to 0.082)	0.367

CI, confidence interval; eGFR, estimated glomerular filtration rate.

^aMultivariable adjustment for sex (male/female), age (years), eGFR and urine protein/creatinine ratio.

*Plasma suPAR values were measured by suPARnostic™ assay.

**Plasma suPAR values were measured by Quantikine Human uPAR ELISA Kit.