Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Sep 24;9:13753. doi: 10.1038/s41598-019-50276-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Increase in anticancer-induced toxicity by chrysin in a spheroid model. RERF-LC-AI cells were plated on PrimeSurface96V multi-well plates, and then treated with or without 10 μM chrysin (Chr) for 24 h. (A,B) The spheroid size and fluorescence intensity of LOX-1 are represented as a percentage of the values in the control (Cont). (C) The cells were incubated with DXR for 60 min at the concentrations indicated. The fluorescence intensities of DXR in spheroids are shown as a percentage of the values in 0 μM. (D,E) After treating the cells with DXR or CDDP for 24 h at the concentrations indicated, the viability of spheroid cells was measured. These values are represented as a percentage of the control. n = 3–4. *P < 0.05 and NS, P > 0.05 compared with the control.