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Figure 3.

Figure 3

Effect of YHD and EYHD pre-treatment on collagen-induced platelet aggregation in vitro and ex vivo. (A-D) Washed platelets (3.0 × 108 cells/ml) were incubated with the indicated drugs for 5 min at 37 °C and subsequently platelet aggregation was induced with 5 μg/ml collagen in vitro (n = 6). Blood was drawn 2 h following YHD or EYHD gavage. (E) Washed platelets (3.0 × 108 cells/ml) were induced aggregation with 5 μg/ml collagen ex vivo (n = 6). * p < 0.05 and ** p < 0.01 vs. control. ASP, aspirin; EYHD, ethanol-precipitated YHD; YHD, YiqiHuoxue decoction.