Figure 4.

Effect of YHD and EYHD on FeCl₃-induced mesenteric arterial thrombosis in vivo and bleeding in rat tail. (A-B) Mouse mesenteric artery was exposed and in contact with a filter paper saturated with 4% FeCl₃ solution for 2 min. The mesenterium was observed for 40 min under an inverted microscope. (A) Real-time recording of thrombosis in each group (white arrow indicates the direction of blood flow). (B) Onset of FeCl₃-induced mesenteric arterial thrombosis in YHD- and 75% EYHD-treated mice (n=6). (C) After anesthesia, the rat’s tail tip was transected 3 mm from the end after which the time taken for bleeding to cease was recorded (n = 6). * p < 0.05 and ** p < 0.01 vs. control. ASP, aspirin; EYHD, ethanol-precipitated YHD; YHD, YiqiHuoxue decoction.