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. 2019 Sep 24;9:13791. doi: 10.1038/s41598-019-50232-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Jaccard index and localization error (accuracy). (a) Jaccard index, (b) localization errors for BAMF, FALCON and single-emitter fitting using 2,000 and 500 photons per frame. (c) The intensity priors used to analyze the data. To make these plots for BAMF, the MAPN was used from RJMCMC. (d) represents the ability of BAMF, FALCON and SRRF to distinguish two nearby emitters with different separations. Row A shows a frame of simulated data with different separations. Rows B, C and D result from emitters with 2,000 photons, and rows E, F and G show the results from 500 photon emitters. The BAMF super-resolved images are the posterior images containing all the possible models. The scale bars are σ_PSF.