Table 2.
Results of the miRNA expression analysis.
| miRNA | Mean difference (95% CI) | p-value | |
|---|---|---|---|
| PD vs. controls | miR-885-5p | 2.58 (1.37, 3.79) | <0.001 |
| miR-361-5p | −3.31 (−4.93, −1.7) | 0.036 | |
| miR-17-5p | 2.48 (1.28, 3.68) | 0.034 | |
| Early stage PD patients vs. controls | miR-885-5p | 2.25 (0.15, 4.36) | 0.034 |
| miR-361-5p | −4.95 (−7.71, −2.19) | <0.001 | |
| miR-17-5p | 1.72 (−0.35, 3.79) | 0.116 | |
| Advanced stage PD patients vs. controls | miR-885-5p | 3.67 (0.79, 6.55) | 0.009 |
| miR-361-5p | 1.75 (−1.60, 5.10) | 0.332 | |
| miR-17-5p | 4.93 (2.25, 7.62) | <0.001 | |
| Advanced stage PD patients vs. Early stage PD patients | miR-885-5p | 1.41 (−1.27, 4.10) | 0.416 |
| miR-361-5p | 6.70 (3.06, 10.34) | 0.023 | |
| miR-17-5p | 3.22 (0.45, 5.98) | 0.021 |
Abbreviations: CI = confidence interval; miRNA = microRNA; PD = Parkinson’s disease. The results are referred to the expression data elaborated using a reference gene miR-191-5p.