Table 1:

genes that participate in AMH GRN for Müllerian duct regression

Gene	Mutation	Phenotype	Reference
Acvr1	Conditional KO	Normal MD regression	Orvis et al. [36]
Amh	Null	PMDS	Behringer [21]; Arango et al. [22]
Amhr2	Null	PMDS	Mishina et al. [30]; Jamin et al. [31]; Arango et al. [17]
Bmpr1a	Conditional KO	PMDS	Jamin et al. [31]; Orvis et al. [36]
Ctnnb1 (beta-catenin)	Conditional KO	PMDS	Kobayashi et al. [41]
Gata4	Binding site mutant or deletion	Normal MD regression	Bouchard et al. [26]
Mmp2	Null	Normal MD regression	Roberts et al. [44]
Smad1/5/8	Conditional KO	PMDS	Orvis et al. [36]
Sp7 (Osterix)	Null	Delayed MD regression	Mullen et al. [42]
Wif1	Null	Normal MD regression	Park et al. [46]
Wnt7a	Null	PMDS	Parr and McMahon [34]

Conditional KO, Müllerian duct mesenchyme-specific knockout; MD, Müllerian duct; null, full body knockout; PMDS, persistent Müllerian duct syndrome.