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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: J 3D Print Med. 2019 Jan 15;3(1):11–22. doi: 10.2217/3dp-2018-0017

Figure 4. Effects of extrusion pressure on viability of constructs printed using cardiac myocyte- and cardiac fibroblast-laden gelatin methacryloyl bioinks.

Figure 4.

Daily change in values of BLI from 3D printed constructs containing cells transfected with luciferin luciferase. The BLI Units are ph/sec/cm2/sr. The slope of BLI/pressure relationship quantifies the difference between sensitivity of CMC- and CFB-laden constructs to sheer stress caused by high extrusion pressures. In CMC-laden constructs, high extrusion pressures led to a loss of viable cells which manifested as a negative value of daily BLI changes.

BLI: Bioluminescence intensity; CFB: Cardiac fibroblast; CMC: Cardiac myocyte; GelMA: Gelatin methacryloyl.