. 2019 Jul 2;160(10):2367–2387. doi: 10.1210/en.2019-00194

Table 5.

mRNA Expression in Skeletal Muscle

Genes	Sig.	M Veh	M Cort	F Veh	F Cort
GR, MR, and GR target genes
Nr3c1	—	1.00 ± 0.17	0.90 ± 0.06	0.88 ± 0.20	0.91 ± 0.15
Fkbp5	S,C,×	1.00 ± 0.10	18.11 ± 1.06^a	0.69 ± 0.13	12.49 ± 2.29^a^,^b
Tsc22d3	C	1.00 ± 0.20	3.99 ± 0.67^a	1.07 ± 0.21	4.30 ± 0.95^a
Nr3c2	—	1.00 ± 0.10	1.36 ± 0.29	1.22 ± 0.34	1.21 ± 0.13
Muscle atrophy
Foxo1	C	1.00 ± 0.13	12.80 ± 2.11^a	1.30 ± 0.30	14.25 ± 3.46^a
Klf15	C	1.00 ± 0.18	2.70 ± 0.63^a	1.22 ± 0.24	2.23 ± 0.36
Glucose transport
Irs1	S,C,×	1.00 ± 0.17	0.66 ± 0.10	2.24 ± 0.45^b	0.61 ± 0.19^a
Slc2a1	—	1.00 ± 0.27	1.60 ± 0.61	1.08 ± 0.13	0.81 ± 0.26
Slc2a4	—	1.00 ± 0.08	1.04 ± 0.09	1.01 ± 0.16	1.24 ± 0.12
Chrebpb	C	1.00 ± 0.35	13.06 ± 1.22^a	0.80 ± 0.06	18.04 ± 10.57^a

Gene expression was normalized to Gapdh and Rn18s expression and expressed relative to the vehicle-treated male mice. Sig. indicates significant effects (P < 0.05) analyzed with two-way ANOVA.

Abbreviations: C, corticosterone treatment; S, sex; ×, interaction of corticosterone treatment and sex.

^{^a}

P < 0.05, for effect of corticosterone treatment in mice of the same sex, by post hoc test.

^{^b}

P < 0.05, for sex difference between mice with the same treatment, by post hoc test.