Figure 4.
Effects of GH gene disruption on organ size, liver triglyceride content, and liver histology. Organ mass relative to body mass in 6-mo-old (A) males and (B) females (n = 8 to 11). Organ mass relative to body length in 6-mo-old (C) males and (D) females (n = 8 to 11). Triglyceride content and liver histology in liver tissue from 6-mo-old (E–G) males and (H–J) females (n = 8 to 11). Liver images are shown at ×400 magnification. Vertical bars represent standard error. *P < 0.05, significantly different from WT controls. Gastroc, gastrocnemius; Int, intestine; L, large; Quad, quadriceps; S, small; TG, triglyceride.