Scheme 2. Scope of the Reaction,
Reaction conditions: 2aa–o (0.20 mmol), Pd2(dba)3 (0.01 mmol). L4 (0.04 mmol) in dioxane (8 mL; 0.025 M) at rt.
Determined by chiral SFC analysis.
1.0 mmol scale reaction.
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