Table 3.
Receiver operating characteristic curve analysis for prediction of need for massive transfusion using each factor at the scene in cohort 1 + 2.
| A. Univariate | |||||
|---|---|---|---|---|---|
| Variable | AUC (95% CI) | P value | Cut-off value | Sensitivity, specificity | OR (95% CI) |
| Lactate | 0.764 (0.661–0.867) | <0.0001 | 3.1 | 0.647, 0.835 | 9.08 (8.70–9.46) |
| Systolic blood pressure | 0.713 (0.607–0.819) | 0.00073 | 93 | 0.441, 0.955 | 16.48 (16.06–4.01) |
| Heart rate | 0.651 (0.539–0.764) | 0.023 | 100 | 0.529, 0.766 | 3.65 (3.29–4.01) |
| Respiratory rate | 0.530 (0.406–0.654) | 0.73 | 24 | 0.618, 0.576 | 2.16 (1.80–2.52) |
| Glasgow Coma Scale | 0.796 (0.718–0.874) | <0.0001 | 8 | 0.559, 0.910 | 12.60 (12.22–12.98) |
| Shock index | 0.763 (0.663–0.862) | <0.0001 | 0.95 | 0.529, 0.910 | 11.23 (10.85–11.61) |
| B. Multivariate | |||||
| Variable | AUC (95% CI) | P value | Sensitivity, specificity | OR (95% CI) | |
| Physiological variablesα | 0.895 (0.846–0.944) | <0.0001 | 0.853, 0.820 | 24.38 (23.89–24.86) | |
| Physiological variablesα plus lactate level at the scene | 0.903 (0.851–0.956) | <0.0001 | 0.941, 0.748 | 38.48 (37.82–39.15) | |
AUC, area under the curve; CI, confidence interval; OR, odds ratio.
αPhysiological variables include systolic blood pressure, heart rate, respiratory rate, Glasgow Coma Scale score, shock index score at the scene, and positive mechanism of penetrating injury.