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. 2019 Jul 11;26(7-8):338–346. doi: 10.1038/s41434-019-0091-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Detection of plasmid sequences by visualization of reads that cannot be aligned to the EPO reference gene in the IGV viewer. Sequencing reads that contain both EPO copyDNA and plasmid sequence are shown as partially mismatched reads by visualization of the alignment to EPO gDNA in the IGV browser. This allows distinction of EPO gDNA and EPO copyDNA