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. 2019 Feb 13;85(7):1001–1007. doi: 10.1038/s41390-018-0263-x

Table 1.

Subject information

Subject ID GA (weeks) CGA at scan (weeks) Respiratory Neurology Diagnosis/MRI findings DOT channels incl. (%)
Stroke_1 38 + 4 38 + 6 HFNC Apneas, Seizures

Perinatal stroke

Large hemorrhagic lesion in the left temporal lobe associated with overlying subdural hemorrhage; secondary to venous infarction

82.76
Stroke_2 37 + 2 37 + 3 SIMV+VG Seizures

Left MCA infarct, HIE II

Abnormal signal intensities within the territory of the left MCA consistent with infarction. Involvement of the basal ganglia, thalami, and PLIC on the left with abnormal diffusion in the Left cerebral peduncle

79.31
Stroke_3 40 40 + 3 SVIA Seizures

Right MCA infarct

Large infarct over the right hemisphere, involving the temporal, parietal, and occipital lobe

79.31
Stroke_4 41 + 3 41 + 6 SVIA Seizures

Left MCA infarct

Abnormal signal intensity within white matter, cortex, and basal ganglia within the territory of the left MCA consistent with infarction

89.66
CTRL_1 37 + 5 38 SVIA Normal Healthy, no MRI 72.41
CTRL_2 40 + 1 40 + 2 SVIA Normal Healthy, no MRI 93.10
CTRL_3 31 + 5 34 + 3 SVIA Normal Healthy, no MRI 48.28
CTRL_4 37 + 2 37 + 3 SVIA Normal Healthy, no MRI 93.10

Clinical details of the stroke-affected and control infants (CTRL)

CGA corrected gestational age, DOT diffuse optical tomography, GA gestational age, HFNC high flow nasal cannula, HIE hypoxic ischemic encephalopathy, MCA middle cerebral artery, MRI magnetic resonance imaging, PLIC posterior limb of the internal capsule, SIMV+VG synchronized intermittent mandatory ventilation with volume guarantee, SVIA self-ventilating in air