Table 1.
Subject ID | GA (weeks) | CGA at scan (weeks) | Respiratory | Neurology | Diagnosis/MRI findings | DOT channels incl. (%) |
---|---|---|---|---|---|---|
Stroke_1 | 38 + 4 | 38 + 6 | HFNC | Apneas, Seizures |
Perinatal stroke Large hemorrhagic lesion in the left temporal lobe associated with overlying subdural hemorrhage; secondary to venous infarction |
82.76 |
Stroke_2 | 37 + 2 | 37 + 3 | SIMV+VG | Seizures |
Left MCA infarct, HIE II Abnormal signal intensities within the territory of the left MCA consistent with infarction. Involvement of the basal ganglia, thalami, and PLIC on the left with abnormal diffusion in the Left cerebral peduncle |
79.31 |
Stroke_3 | 40 | 40 + 3 | SVIA | Seizures |
Right MCA infarct Large infarct over the right hemisphere, involving the temporal, parietal, and occipital lobe |
79.31 |
Stroke_4 | 41 + 3 | 41 + 6 | SVIA | Seizures |
Left MCA infarct Abnormal signal intensity within white matter, cortex, and basal ganglia within the territory of the left MCA consistent with infarction |
89.66 |
CTRL_1 | 37 + 5 | 38 | SVIA | Normal | Healthy, no MRI | 72.41 |
CTRL_2 | 40 + 1 | 40 + 2 | SVIA | Normal | Healthy, no MRI | 93.10 |
CTRL_3 | 31 + 5 | 34 + 3 | SVIA | Normal | Healthy, no MRI | 48.28 |
CTRL_4 | 37 + 2 | 37 + 3 | SVIA | Normal | Healthy, no MRI | 93.10 |
Clinical details of the stroke-affected and control infants (CTRL)
CGA corrected gestational age, DOT diffuse optical tomography, GA gestational age, HFNC high flow nasal cannula, HIE hypoxic ischemic encephalopathy, MCA middle cerebral artery, MRI magnetic resonance imaging, PLIC posterior limb of the internal capsule, SIMV+VG synchronized intermittent mandatory ventilation with volume guarantee, SVIA self-ventilating in air