Table 2.

Selection of different central (e.g., mean) and upper (e.g., 95th percentile) parameter values for alternative scenario evaluation

Scenario	Intake rate	Breastfeeding duration	Half-life	Transfer rates	Volume of distribution (Vd)	Vd adjustment factor
MDH RME	Upper	Upper	Central	Central	Central	Central
Alternative 1	Central	Central	Upper	Upper	Central	Central
Alternative 2	Upper	Central	Upper	Central	Central	Central
Alternative 3	Central	Upper	Upper	Central	Central	Central

See Table 1 for actual numerical values used for each parameter