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. 2019 Jun 3;99(9):1309–1320. doi: 10.1038/s41374-019-0263-4

Fig. 2.

Fig. 2

2H and 5H cells stably express MDM2 and/or CDK4 and display morphologic changes. a The expression of proteins of MDM2 and/or CDK4 was measured by immunoblotting. ◀, 3XFLAG-MDM2 or CDK4; ◁, MDM2 or CDK4. Fold changes were determined by comparing the protein levels to the β-actin levels using ImageJ. b Morphologic changes were assessed by the comparison of protein expression in different cell lines