Table 3.

Cox-regression analysis of the presence of visit-to-visit systolic blood pressure variability for adverse outcomes

Variables	MACEs			All-cause mortality			Recurrent MI			TVR
	Adjusted HR	95% CI	p-Value	Adjusted HR	95% CI	p-Value	Adjusted HR	95% CI	p-Value	Adjusted HR	95% CI	p-Value
Age	1.039	1.016–1.061	0.001	1.095	1.061–1.131	<0.001	0.993	0.955–1.034	0.749	0.987	0.961–1.014	0.339
Gender	1.038	0.53–2.035	0.913	0.957	0.429–2.137	0.915	0.619	0.163–2.347	0.48	1.242	0.494–3.123	0.645
Mean SBP during follow-up	1.003	0.995–1.01	0.51	1.004	0.993–1.015	0.476	0.998	0.978–1.018	0.856	1.002	0.993–1.01	0.661
Diabetes mellitus	1.612	0.933–2.786	0.087	2.047	1.043–4.017	0.037	1.018	0.347–2.986	0.974	1.3	0.657–2.57	0.451
Dyslipidemia	0.562	0.202–1.566	0.271	3.184	0.631–16.075	0.161	0.605	0.074–4.948	0.639	1.087	0.346–3.42	0.886
Smoking	1.379	0.769–2.471	0.28	1.654	0.783–3.493	0.187	1.37	0.41–4.576	0.609	1.081	0.512–2.284	0.837
Killip classification	1.021	0.776–1.342	0.884	1.004	0.723–1.396	0.98	0.289	0.083–1.007	0.051	1.098	0.772–1.562	0.603
LVEF	0.98	0.959–1.0	0.053	0.958	0.932–0.986	0.004	0.992	0.952–1.033	0.697	1.013	0.987–1.038	0.335
BPV ≥ 12.3 mmHg	1.722	1.083–2.738	0.022	1.734	0.936–3.214	0.08	2.308	0.9–5.917	0.082	1.201	0.671–2.15	0.538

MACEs major adverse cardiovascular events, SBP systolic blood pressure, LVEF left ventricular ejection fraction, BPV blood pressure variability, MI myocardial infarction, TVR target vessel revascularization, CI confidence interval, E7 10⁷