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. 2019 Sep 25;14(9):e0222164. doi: 10.1371/journal.pone.0222164

Table 3. Patient characteristics at admission according to survival or death (n = 305).

Parameters All Patients
MD [Q1;Q3] or n, (range: min-max) or (% of all patients)
Survivals
MD [Q1;Q3] or n, (range: min—max)
or (% of Survivals)
Deaths
MD [Q1;Q3], (range: min—max)
or (% of Deaths)
P
Significance
 Patients 305 213 92 NA
 Age (y) 60 [49;72] (range: 18–90) 58 [45;69], (range: 18–89) 63 [54;73], (range: 21–90) 0.0033*
 Sex, n(%) ♂ 184(60.3%) ♂128 (60.1%) ♂ 56 (60.8%) 1.0000°
♀ 121(39.7%) ♀85 (39.9%) ♀ 36 (39.1%)
 Body Mass Index (kg/m2) 25.7[22.1;29.0](range: 13.6–70.3) 25.4 [21.8; 28.9], (range: 13.6–48.2) 25.7 [23.3; 29.3], (range: 13.6–70.3) 0.4880*
Chronic diseases / Co-morbidities
 CKD 131(43.0%) 86 (40.4%) 45 (48.9%) 0.2075°
 Cirrhosis § 68 (22.3%) 30 (14.2%) 38 (41.8%) <0.0001°
 Solid Organ Transplantation 55 (18.0%) 41 (19.3%) 14 (15.2%) 0.5164°
 Cancer & Cancer Therapy§ 15 (4.9%) 10 (4.7%) 5 (5.5%) 0.7768°
 Chronic Heart Failure (NYHA IV) § 10 (3.3%) 4 (1.9%) 6 (6.6%) 0.0711°
 Hematological Cancer § 6 (2.0%) 4 (1.9%) 2 (2.2%) 1.0000°
 AIDS § 4 (1.3%) 3 (1.4%) 1 (1.1%) 1.0000°
Acute conditions
 AKI 97 (31.8%) 57 (26.8%) 40 (43.5%) 0.0049°
 Cardiac Arrhythmias § 52 (17.1%) 35 (16.4%) 17 (18.7%) 0.6218°
 Liver Failure § 50 (16.5%) 19 (8.9%) 31 (34.1%) <0.0001°
 Sepsis 43 (14.1%) 16 (7.5%) 27 (29.4%) <0.0001°
 Nosocomial Infection § 26 (8.5%) 16 (7.5%) 10 (10.9%) 0.3732°
 Vigilance Disturbances § 26 (8.5%) 17 (8.0%) 9 (9.9%) 0.6550°
 Respiratory Insufficiency with NIV 17 (5.6%) 12 (5.8%) 5 (5.5%) 1.0000°
 Septic Shock § 15 (4.9%) 11(5.2%) 4(4.4%) 1.0000°
 Digestive Illnesses (e.g. severe pancreatitis, acute abdomen) § 11 (3.6%) 10 (4.7%) 1 (1.1%) 0.1832°
 Gastrointestinal Bleedings 10 (3.3%) 9 (4.2%) 1 (1.1%) 0.2918°
 Focal Neurological Deficits § 3 (1.0%) 3 (1.4%) 0 0.5568°
Therapeutic interventions at admission
 Vasoactive Drugs § 188 (61.6%) 133 (62.7%) 55 (59.8%) 0.7000°
 Hemodialysis 70 (23.0%) 41 (19.3%) 29 (31.5%) 0.0257°
 NIV 17 (5.6%) 12 (5.8%) 5 (5.5%) 1.0000°
Stay in the ImCU (d) 6[3;14], (range: 0–115) 6 [3; 14], (range: 0–115) 7 [3; 22], (range: 1–67) 0.1197*
SAPS 2 30 [22;39], (range: 6–69) 27 [19; 36], (range: 6–65) 37.5 [27.5; 47.0], (range: 13–69) <0.0001*
SAPS 2 predicted mortality 10.6% [4.7;23.0], (range: 0.5–80.6) 7.9% [3.3; 18.1], (range: 0.5–76.9) 20.5% [8.4; 39.2], (range: 1.5–82.6) <0.0001*
SAPS 3 55[46;64], (range: 24–90) 51 [44; 59], (range: 24–88) 63 [57; 71], (range: 39–90) <0.0001*
SAPS 3 predicted mortality 26.0% [12.0;44.0], (range: 1.0–85.0) 19.0% [10.0; 34.0], (range: 1.0–83.0) 42.0% [30.0; 58.0], (range: 6.0–85.0) <0.0001*

MD = median, Q1 = first quartile, Q3 = third quartile, n = count, CKD = chronic kidney disease, AKI = acute kidney injury, NIV = non-invasive ventilation

§ = part of the SAPS 2 or SAPS 3 scoring system

NA = not applicable

* = Mann-Whitney U test

° = Fisher’s exact test