Table 2.

Review results. The changes of corneal sensibility, thickness, and intraocular pressure during the menstrual cycle and pregnancy

Physiologic state	Author, reported year (article number)	Participants	Results
Menstruation	Riss B, et al. 1982 (4)	5 healthy women	CTT rose in 4 women with proved ovulation in the days before or on the day of ovulation.
	Kiely PM, et al. 1983 (5)	(The second study) 2 women	Slight deacrease in corneal thickness was evident toward the end of menses, and increased at ovulation compared with pre-ovulation. Also, increased during early luteal phase.
	Ghahfarokhi NA, et al. 2015 (6)	50 healthy women	The thickest cornea during the menstrual cycle at ovulation, and the thinnest occurred at the end of the cycle.
Pregnancy	Millodot M, et al. 1977 (7)	30 non-pregnant women 29 pregnant women	Most pregnant women tended to have a higher CTT with advancing pregnancy.
	Riss B, et al. 1981 (8)	86 pregnant women	The thresholds were significantly higher among pregnant women compared to the non-pregnant group.
	Tolunay HE, et al. 2016 (9)	235 pregnant women	The mean intraocular pressures were significantly higher in the first trimester and puerperal period than in the third trimester.
	Efe YK, et al. 2012 (10)	25 pregnant women	The mean intraocular presssue in the second and third trimesters of pregnancy were found to be lower than those in the first trimester and at 3 months postpartum. The mean central corneal thickness in the second and third trimester of the pregnancy was measured to be higher than in the first trimester and at 3 months post partum.