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. 2019 Sep 24;57(10):e00547-19. doi: 10.1128/JCM.00547-19

TABLE 1.

Agreement between MTTT and CTTT strategies overall and by symptom stage

Stage (n) MTTT result CTTT result
% Agreement (95% CI) Kappa (95% CI)
Positive Negative
Overall (1,066) Positive 144 21 96.9 (95.7–97.8) 0.88 (0.84–0.92)
Negative 12 889
Erythema migrans lesion (21) Positive 3 1 95.2 (77.3–99.2) 0.83 (0.51–1.00)
Negative 0 17
Symptoms of early disseminated Lyme disease (371) Positive 45 10 95.7 (93.1–97.3) 0.82 (0.74–0.90)
Negative 6 310
Symptoms of late Lyme disease (674) Positive 96 10 97.6 (96.2–98.5) 0.91 (0.87–0.95)
Negative 6 562