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. 2019 Sep 24;57(10):e00547-19. doi: 10.1128/JCM.00547-19

TABLE 3.

Clinical and serologic information from children with positive modified two-tiered testing and negative conventional two-tiered testing (n = 21)a

Suspected stage of Lyme disease Age (yr) Symptom duration ≤30 days eIA
Band(s) (kDa)
Classification Subcategoryc
WCS C6 IgG IgM
Early 6 Y 1.99 1.35 41 None PSC PSC1
Early disseminated 2 Y 1.10 0.98 41 None FPM FPM5
3 Y 1.96 1.49 58, 41 None FPM FPM5
4 N 1.01 1.52 66, 41 None FPM FPM4
9 N 1.11 1.10 41 None FPM FPM1
11 Y 1.72 1.06 41 None FPM FPM5
11 N 1.13 1.35 41, 23 41, 23 FPM FPM6
12 N 1.18 1.05 41 None FPM FPM1
13 N 2.41 2.15 41, 39, 18 None PSR PSR6
15 N 4.26 6.50 66, 41, 23 41, 39, 23 PSC PSC3
16 N 1.59 5.40 None 41, 23 PSC PSC3
Late 2 Y 1.97 3.01 41, 39 None FPM FPM3
3 Y 4.29 6.69 45, 41 None FPM FPM2
5b Y 1.11 1.23 41 None PSC PSC2
6 N 2.42 5.07 93, 58, 39, 18 41 PSR PSR6
8 N 1.06 3.12 66, 41, 23, 18 None PSR PSR6
9 N 1.08 1.02 41 None FPM FPM4
11 Y 4.68 1.16 66, 41 None FPM FPM3
13 N 1.01 0.99 None None FPM FPM4
15 Y 1.22 1.04 None None FPM FPM4
17 N 1.07 1.04 39 None FPM FPM4
a

PSC, partial seroconversion; PSR, partial seroreversion; FPM, false-positive MTTT.

b

This child had a recent history of physician-diagnosed erythema migrans.

c

See the supplemental material for category descriptions.