Table 1. Baseline characteristics of cases and controls [median (min–max) or N (%)].
| Cases (N = 156) | Controls (N = 213) | Pa | |
|---|---|---|---|
| Men / Women | 85 (53%) / 74 (47%) | 115 (53%) / 102 (47%) | |
| Age at blood draw, years | 58.1 (34.9-75.7) | 58.0 (34.5-75.4) | |
| BMI, kg/m2 | 26.7 (19.0-38.9) | 26.0 (14.7-40.6) | |
| < 25 | 56 (36) | 84 (39) | 0.067 |
| ≥ 25 | 100 (64) | 129 (61) | |
| Smoking | |||
| Never | 61 (39) | 93 (44) | 0.024 |
| Former | 47 (30) | 77 (36) | |
| Current | 47 (30) | 40 (19) | |
| Unknown | 1 | 3 (1) | |
| Alcohol consumption | |||
| Yes | 133 (85) | 187 (88) | 0.446 |
| Non drinker | 22 (14) | 25 (12) | |
| Unknown | 1 | 1 | |
| Diabetesb | |||
| Yes | 14 (9) | 16 (7) | 0.095 |
| No | 125 (80) | 177 (83) | |
| Unknown | 17 (11) | 20 (10) | |
| Case characteristics | |||
| Age at diagnosis, median (range), years | 60.9 (37.2-79.6) | — | |
| Lag time, median (range), months | 35 (1-60) | — | |
| Morphology of the tumor Adenocarcinoma | 106 (68) | — | |
| Tumor site | |||
| Head | 82 (53) | — | |
| Body | 12 (8) | — | |
| Tail | 8 (5) | — | |
| Unspecific | 54 (35) | — | |
| Disease spread | |||
| Localized | 14 (9) | — | |
| Metastatic | 73 (47) | — | |
| Unknown | 69 (44) | — | |
| Basis of tumor diagnosis | |||
| Microscopically confirmed | 106 (68) | — | |
| Other (i.e. imaging, clinical symptoms) | 50 (32) | — | |
| Markerc | |||
| CA19-9 (U/mL) | 12.1 (10.1-14.6) | 6.8 (6.2-7.4) | 0.101 |
| ApoA2-AT/AT (μg/mL) | 43.2 (37.8-49.4) | 48.7 (45.6-52.0) | 0.480 |
| ApoA2-ATQ/ATQ (μg/mL) | 41.4 (38.7-44.2) | 42.9 (41.1-44.7) | 0.892 |
| ApoA2-ATQ/AT (μg/mL) | 42.2 (39.9-44.7) | 45.7 (44.5-46.8) | 0.193 |
a
P values determined using paired t-tests or generalized McNemar’s test.
b
Self-reported at baseline.
c
Presented as geometric mean (95% CI).
Note: BMI = body-mass-index