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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Aug 22;39(10):2082–2096. doi: 10.1161/ATVBAHA.119.313115

Figure 2. MCDCev reduce infarct size post-MI.

Figure 2.

(A) Schematic of the in vivo protocol used to assess adoptive transfer of Mϕ following ischemia-reperfusion injury in rats. IHC: immunohistochemistry; TTC: 2,3,5-Triphenyl-2H-tetrazolium chloride. (B) Representative images of DiD-labeled Mϕ in the infarct border zone at 4 hours. (C) Representative TTC-stained hearts at 48 hours. (D) Quantification of percent infarct mass from (C). (E) Representative images of TUNEL-stained hearts in the infarct border zone at 48 hours. (F) Quantification of percent TUNEL positive cardiomyocytes (CM) from (E). Graphs depict mean +/− SEM with n=5–6/group. Statistical significance was determined using 1-way ANOVA followed by Holm-Sidak’s multiple corrections test. *p<0.05.