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. Author manuscript; available in PMC: 2019 Sep 25.
Published in final edited form as: Curr Top Med Chem. 2019;19(16):1381–1398. doi: 10.2174/1568026619666190709101449

Fig. (5). Current synthetic 5-HT2CR agonists share similarities in their pharmacophore.

Fig. (5).

(A) The general chemical scheme describing structural requirements for 5-HT2CR agonists is presented. (B) Selected 5-HT2CR agonists are organized based on chemotype. Blue indicates the common aromatic fragment, green indicates the requisite ionizable amine, and magenta highlights the linker.