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. Author manuscript; available in PMC: 2019 Sep 25.
Published in final edited form as: Curr Top Med Chem. 2019;19(16):1381–1398. doi: 10.2174/1568026619666190709101449

Fig. (6). A novel pharmacophore for 5-HT2CR agonists is described.

Fig. (6).

Compound 20 is the result of an intentional screening and optimization study which sought to discover non-traditional 5-HT2CR ligands, as defined by an aromatic ring joined to an amine fragment by a short aliphatic linker [109].