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. Author manuscript; available in PMC: 2019 Sep 25.
Published in final edited form as: Curr Top Med Chem. 2019;19(16):1381–1398. doi: 10.2174/1568026619666190709101449

Fig. (8).

Fig. (8).

(A) The earliest reported small molecules with allosteric modulatory activity at the 5-HT2CR are PNU-69176E (21) and oleamide (22). (B) PNU-69176E is an analogue of the natural product antibiotic lincomycin (23) and a derivative of the clinically available antibiotic clindamycin (24).