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Mankin score (criteria for histological evaluation).
| Item | Grade/classification | Grade |
|---|---|---|
| Structural intergrity | Normal | 0 |
| Irregular Surface | 1 | |
| Pannus formation | 2 | |
| Fissures into transitional layer | 3 | |
| Fissures into emmiting layer | 4 | |
| Fissures into calcified layer | 5 | |
| Complete disorganization | 6 | |
| Cells | Normal | 0 |
| Hypercellularity | 1 | |
| Cloning | 2 | |
| Hypocellularity | 3 | |
| Safranin-O staining | Normal | 0 |
| Slight reduction | 1 | |
| Moderate reduction | 2 | |
| Severe reduction | 3 | |
| No dye noted | 4 | |
| Tidemark intergrity | Normal | 0 |
| Disruption | 1 |
