Table 3.
Phenotype | PPARG | SCAMP3 | ||
---|---|---|---|---|
partial r-value | p-value | partial r-value | p-value | |
Body mass index, kg/m | −0.82 | <0.0001 | 0.76 | <0.00001 |
Body fat, % of total body weight | −0.72 | <0.0001 | 0.73 | <0.0001 |
Waist circumference, cm | −0.78 | <0.0001 | 0.78 | <0.0001 |
Waist-to-hip, ratio cm/cm | −0.58 | 0.0003 | 0.62 | 0.0001 |
Homeostasis model assessment of in vivo insulin sensitivity, arbitrary units* | −0.56 | 0.0003 | 0.62 | 0.0001 |
Fat cell volume, picolitres | −0.83 | <0.0001 | 0.73 | <0.0001 |
Insulin stimulated lipogenesis in fat cells, nmoles of glucose/2 hours/107 fat cells* | 0.43 | 0.017 | −0.56 | 0.002 |
Adipose tissue secretion of interleukin-6, ng/2 hours/107 fat cells* | −0.62 | 0.001 | 0.58 | 0.002 |
Adipose tissue secretion of tumor necrosis factor alpha, ng/2 hours/107 fat cells* | −0.57 | 0.002 | 0.75 | <0.0001 |
Adipose tissue lipolytic activity, µmoles of glycerol/2 hours/107 fat cells*# | −0.66 | 0.007 | 0.42 | 0.025 |
Multiple regression was used. A negative r-value indicates inverse relationship between regressor and phenotype.
*Values were (10) log transformed prior to use. #This is release of glycerol (an end products of triglyceride hydrolysis) into the medium of adipose tissue incubated pieces.