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. 2019 Sep 25;9:13834. doi: 10.1038/s41598-019-50195-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Consistent and distinct TLC lipidome profiles of urinary microvesicles vs. exosomes. After isolation/purification, lipids were extracted from urinary microvesicles and exosomes and then resolved by TLC. The data showed consistent TLC band pattern of each type of these two EVs in all four independent experiments. Moreover, the TLC band pattern of lipids derived from urinary microvesicles obviously differed from those derived from urinary exosomes. The full-length images of these cropped TLC plates are provided in Supplementary Fig. S1. MV = microvesicles; Exo = exosomes.